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Study identifier: NCT07742826 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery

Condition: Impacted Mandibular Third Molar Extraction · Impacted Lower Third Molar · Impacted Wisdom Tooth  ·  Sponsor: Final International University

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing impacted mandibular third molar surgery. A total of 60 participants will be randomly assigned to one of three treatment groups according to the study protocol. Postoperative pain, facial swelling, and trismus will be evaluated on postoperative days 1, 2, 3, and 7. The findings of this study are expected to provide evidence regarding the effectiveness of PRF alone and PRF combined with corticosteroid treatment in reducing postoperative complications following impacted mandibular third molar surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Meliz Kneebone, DDS  ·  +905338425731  ·  meliz-95@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Final International University Faculty of DentistryNicosia, CyprusRecruiting

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