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Study identifier: NCT07742735 Synced from ClinicalTrials.gov · August 03, 2026
● Recruiting

A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)

Condition: Short Bowel Syndrome (SBS) · SBS Associated With Intestinal Failure (SBS-IF)  ·  Sponsor: VectivBio AG

PhasePhase 3
Planned participants124
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This Phase 3 placebo-controlled study is planned to further investigate the efficacy, safety, and tolerability of apraglutide in the overall SBS-IF (short bowel syndrome associated with intestinal failure) population during 24 weeks of study treatment. It is expected that approximately 124 participants will be randomized worldwide to either apraglutide or placebo in a 1:1 ratio in this trial.

This description comes directly from the study's public registry record.

Talk to the study team

Emie Liu, MD  ·  +41 61 551 30 30  ·  clinicaltrialenquiries@ironwoodpharma.com

Always discuss trial participation with your own doctor first.

Locations (94)

Ronald Reagan UCLA Medical Center, Center for the Health SciencesLos Angeles, California, United StatesNot Yet Recruiting
Denver Health Medical CenterDenver, Colorado, United StatesNot Yet Recruiting
MedStar Georgetown University HospitalWashington D.C., District of Columbia, United StatesNot Yet Recruiting
University of Florida Health (UF Health)Gainesville, Florida, United StatesNot Yet Recruiting
GI ProsNaples, Florida, United StatesRecruiting
Cleveland Clinic FloridaWeston, Florida, United StatesNot Yet Recruiting
Loyola University Medical CenterMaywood, Illinois, United StatesNot Yet Recruiting
UofL Physicians - Colon & Rectal SurgeryLouisville, Kentucky, United StatesNot Yet Recruiting
Henry Ford Medical Center - ColumbusNovi, Michigan, United StatesNot Yet Recruiting
Albany Medical CenterAlbany, New York, United StatesNot Yet Recruiting
Mount Sinai Medical Center, RMTI - Intestinal Transplantation & RehabilitationNew York, New York, United StatesNot Yet Recruiting
Duke University Medical CenterDurham, North Carolina, United StatesNot Yet Recruiting

+ 82 more locations — full list on the registry record.

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