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Study identifier: NCT07741071 Synced from ClinicalTrials.gov · August 04, 2026
● Not Yet Recruiting

N-AD: A Randomized, Double Blind, Parallel Group, Placebo Controlled, Phase 2 Trial of Orally Administered Nicotinamide Riboside Over Two Years as a Potential Disease Modifying Treatment for Alzheimer's Disease

Condition: Alzheimer Disease (AD)  ·  Sponsor: Haukeland University Hospital

PhasePhase 2
Planned participants270
Who can joinAll sexes, 50 Years to 85 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if orally administered nicotinamide riboside works to slow the progression of early Alzheimer disease in adults. It will also learn about the safety of drug nicotinamide riboside. The main questions it aims to answer are: * Does drug nicotinamide riboside slow the progression of Alzheimer disease as measured by the Clinical Dementia Rating scale. * What medical problems do participants have when taking drug nicotinamide riboside? Researchers will compare drug nicotinamide riboside to a placebo (a look-alike substance that contains no drug) to see if nicotinamide riboside works to treat early Alzheimer disease. Participants will: * Take drug nicotinamide ribosie or a placebo every day for 24 months * Visit the clinic once every 26 weeks for checkups and tests

This description comes directly from the study's public registry record.

Talk to the study team

Kristoffer Haugarvoll, MD, PhD  ·  47-55975045  ·  kristoffer.haugarvoll@helse-bergen.no

Always discuss trial participation with your own doctor first.

Locations (2)

Haraldsplass Deaconess HospitalBergen, Norway
Haukeland University HospitalBergen, Norway

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