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Study identifier: NCT07738770 Synced from ClinicalTrials.gov · August 03, 2026
● Recruiting

Analgesic Efficacy of Combined PECS II and PIP Block Versus Thoracic Paravertebral Block Post-Mastectomy

Condition: Acute Pain · Post Operative Analgesia · Post Operative Pain, Acute  ·  Sponsor: Dharmais National Cancer Center Hospital

PhaseNA
Planned participants72
Who can joinFemale, 18 Years to 60 Years
Healthy volunteersNo

About this study

Postoperative pain management is crucial for patients undergoing mastectomy for breast cancer. Regional analgesia techniques, such as the Thoracic Paravertebral Block (TPVB), are commonly used to reduce pain and opioid consumption; however, TPVB carries potential risks, including pneumothorax. Interfascial plane blocks, specifically the Pectoral Nerve II (PECS II) block combined with the Superficial Parasternal Intercostal Plane (PIP) block, have emerged as alternative techniques to provide comprehensive analgesia to both the lateral and anterior chest wall. The purpose of this randomized controlled trial is to evaluate and compare the analgesic efficacy and quality of postoperative recovery between a combination of ultrasound-guided PECS II and PIP blocks versus the standard Thoracic Paravertebral Block (TPVB) in patients undergoing mastectomy with or without axillary lymph node dissection (ALND). Participants will be randomly assigned to receive either the combined PECS II and PIP block or the TPVB following general anesthesia induction. Pain scores, total opioid consumption, time to first analgesic request, quality of recovery using the QoR-15 questionnaire, and potential block-related complications will be monitored and compared over the 24-hour postoperative period.

This description comes directly from the study's public registry record.

Talk to the study team

Annisa Annisa, Anesthesiologist  ·  81317235246  ·  annisa157sasa@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Dharmais National Cancer Center HospitalJakarta, DKI Jakarta, IndonesiaRecruiting

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