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Study identifier: NCT07737236 Synced from ClinicalTrials.gov · August 02, 2026
● Recruiting

Ruscus Evaluation for Symptom Control in Uncomplicated Chronic Venous Insufficiency

Condition: Chronic Venous Disease  ·  Sponsor: Turkish Society for Vascular and Endovascular Surgery

PhaseN/A
Planned participants564
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This multicenter, prospective, observational study aims to generate and analyze real-world data on the effectiveness and safety of Ruscus aculeatus L. treatment in patients with symptomatic chronic venous disease classified as CEAP C1-C6. Patients receiving Ruscus aculeatus L. as part of routine clinical practice will be followed for 90 days without any study-mandated intervention. Disease severity will be assessed using the revised Venous Clinical Severity Score (rVCSS), pain using the Visual Analog Scale (VAS), quality of life using the Chronic Venous Disease Quality of Life Questionnaire (CIVIQ-20), treatment adherence using the Visual Analog Scale for adherence (VAS-U), and safety through the collection of adverse events during the observation period.

This description comes directly from the study's public registry record.

Talk to the study team

Nevzat Erdil, MD  ·  +90 532 427 18 20  ·  nevzatkutay@gmail.com

Always discuss trial participation with your own doctor first.

Locations (25)

Ankara Training and Research HospitalAnkara, Ankara, Turkey (Türkiye)Recruiting
Ankara University Faculty of Medicine HospitalAnkara, Ankara, Turkey (Türkiye)Recruiting
Bilkent City HospitalAnkara, Ankara, Turkey (Türkiye)Recruiting
Etlik City HospitalAnkara, Ankara, Turkey (Türkiye)Recruiting
Gazi University Faculty of Medicine HospitalAnkara, Ankara, Turkey (Türkiye)Not Yet Recruiting
SBU Gulhane Training and Research HospitalAnkara, Ankara, Turkey (Türkiye)Recruiting
SBU Sincan Training and Research HospitalAnkara, Ankara, Turkey (Türkiye)Recruiting
Yıldırım Beyazıt University Yenimahalle Training and Research HospitalAnkara, Ankara, Turkey (Türkiye)Recruiting
Gaziantep University Faculty of Medicine HospitalGaziantep, Gaziantep, Turkey (Türkiye)Not Yet Recruiting
Mustafa Kemal University HospitalAntakya, Hatay, Turkey (Türkiye)Not Yet Recruiting
Bagcilar Training and Research HospitalIstanbul, Istanbul, Turkey (Türkiye)Recruiting
Bahcelievler State HospitalIstanbul, Istanbul, Turkey (Türkiye)Recruiting

+ 13 more locations — full list on the registry record.

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