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Study identifier: NCT07735039 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

Dual-Modality Immunotherapy for HPV Clearance (DUAL-HPV)

Condition: Human Papillomavirus Infection · Cervical Intraepithelial Neoplasia (CIN) · Low-Grade Squamous Intraepithelial Lesions  ·  Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital

PhaseNA
Planned participants76
Who can joinFemale, 18 Years to 65 Years
Healthy volunteersNo

About this study

Persistent high-risk human papillomavirus infection is an important precursor of cervical cancer and related cervical lesions. This single-center, randomized, assessor-blinded, parallel-group controlled trial evaluates whether dual-modality immunotherapy consisting of an oral immunomodulator plus a vaginal ovule improves HPV clearance compared with standard supportive care. A total of 76 participants will be randomized in a 1:1 ratio. The primary outcome is HPV clearance confirmed by repeat HPV testing and cervical cytology after the 3-month treatment period. Treatment adherence and adverse events will also be monitored.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (1)

University of Health Sciences Turkey, Kartal Dr. Lütfi Kırdar City HospitalIstanbul, Istanbul, Turkey (Türkiye)

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