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Study identifier: NCT07731490 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

Early Detection and IntervenTion in Heart Failure

Condition: Heart Failure (HF)  ·  Sponsor: University Hospital, Basel, Switzerland

PhaseNA
Planned participants18000
Who can joinAll sexes, 65 Years to no upper limit
Healthy volunteersNo

About this study

Heart failure (HF) occurs when the heart is no longer able to pump blood effectively throughout the body. This leads to symptoms that gradually worsen over time and are often mistaken for normal signs of aging. Because of its insidious onset, early detection is challenging. Both patients and healthcare professionals are often insufficiently aware of the early signs and symptoms of HF, resulting in delayed diagnosis. Consequently, timely initiation of treatments that could slow disease progression, improve quality of life, and reduce hospitalizations is often missed. Although a simple blood test measuring NT-proBNP levels can facilitate the early diagnosis of HF, it is not routinely used in clinical practice. The aim of this study is to evaluate whether a combined strategy for the early diagnosis and treatment of HF can reduce hospitalizations. This strategy includes: 1. increasing awareness of HF among patients and physicians, 2. using NT-proBNP testing for the early detection of HF in high-risk patients, and 3. promptly initiating guideline-directed HF treatment when the diagnosis is confirmed. The researchers will assess whether this strategy effectively reduces hospitalizations due to acute heart failure over an 18-month follow-up period.

This description comes directly from the study's public registry record.

Talk to the study team

Christian Müller, Prof. Dr.  ·  +41 61 328 65 49  ·  Christian.Mueller@usb.ch

Sonja Horvat, Dr.  ·  sonja.horvat-csoti@usb.ch

Always discuss trial participation with your own doctor first.

Locations (21)

Universitätsklinik für Innere Medizin IIVienna, AustriaNot Yet Recruiting
Queen Giovanna University HospitalSofia, BulgariaNot Yet Recruiting
University Hospital Freiburg-Bad KrozingenFreiburg im Breisgau, GermanyNot Yet Recruiting
Universitätsklinikum der Ruhr-Universität BochumHerne, GermanyNot Yet Recruiting
Herzzentrum Leipzig, Klinik für Innere Medizin/KardiologieLeipzig, GermanyNot Yet Recruiting
University Hospital PisaPisa, ItalyNot Yet Recruiting
Erasmus MC RotterdamRotterdam, NetherlandsNot Yet Recruiting
Konkuk University Medical CenterSeoul, South KoreaRecruiting
University Hospital Ramón y Cajal MadridMadrid, SpainNot Yet Recruiting
University Hospital BaselBasel, Basel, SwitzerlandRecruiting
University Hospital LausanneLausanne, Lausanne, SwitzerlandNot Yet Recruiting
KSA Kantonsspital AarauAarau, SwitzerlandNot Yet Recruiting

+ 9 more locations — full list on the registry record.

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