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Study identifier: NCT07712731 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

HPP737 in Adult Patients With Plaque Psoriasis

Condition: Psoriasis  ·  Sponsor: Newsoara Biopharma Co., Ltd.

PhasePhase 3
Planned participants607
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if drug HPP737 works to treat moderate-to-severe plaque psoriasis in adults. It will also learn about the safety of drug HPP737. The main questions it aims to answer are: Does drug HPP737 improve psoriasis severity compared to an active control drug, as measured by the proportion of patients achieving a significant reduction in the Psoriasis Area and Severity Index (PASI) score and other standardized assessments? What medical problems do participants have when taking drug HPP737? Researchers will compare drug HPP737 to an active control drug (a positive drug comparator) to see if drug HPP737 works to treat moderate-to-severe plaque psoriasis. This is a multicenter, randomized, double-blind, double-dummy, active-controlled Phase III clinical trial. Participants will: Take drug HPP737 or an active control drug orally every day Visit the clinic regularly for checkups and tests throughout the study Have their psoriasis severity assessed using standardized scoring tools, including the Psoriasis Area and Severity Index (PASI), static Physician's Global Assessment (sPGA), and Body Surface Area (BSA) The trial plans to enroll approximately 606 participants across about 61 centers in China. Eligible participants are adults aged 18 years and older with a confirmed diagnosis of stable moderate-to-severe plaque psoriasis for at least 6 months.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (60)

Inner Mongolia Baogang HospitalBaotou, China
Beijing Friendship Hospital, Capital Medical UniversityBeijing, China
Beijing Tongren Hospital, Capital Medical UniversityBeijing, China
Beijing Tsinghua Changgung HospitalBeijing, China
Peking University People's HospitalBeijing, China
Cangzhou People's HospitalCangzhou, China
The Second Hospital of Jilin UniversityChangchun, China
Changde First People's HospitalChangde, China
Third Xiangya Hospital of Central South UniversityChangsha, China
The Second People's Hospital of ChangzhiChangzhi, China
Affiliated Hospital of Chengde Medical CollegeChengde, China
Chengdu Second People's HospitalChengdu, China

+ 48 more locations — full list on the registry record.

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