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Study identifier: NCT07712705 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

HPP737 in Adult Patients With Moderate-to-severe Plaque Psoriasis.

Condition: Psoriasis  ·  Sponsor: Newsoara Biopharma Co., Ltd.

PhasePhase 3
Planned participants515
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if drug HPP737 works to treat moderate-to-severe plaque psoriasis in adults. It will also learn about the safety of drug HPP737. The main questions it aims to answer are: Does drug HPP737 improve psoriasis severity compared to a placebo at Week 16, as measured by the proportion of patients achieving a significant reduction in the Psoriasis Area and Severity Index (PASI) score? What medical problems do participants have when taking drug HPP737? Researchers will compare drug HPP737 to a placebo (a look-alike substance that contains no drug) to see if drug HPP737 works to treat moderate-to-severe plaque psoriasis. This is a multicenter, randomized, double-blind, placebo-controlled Phase III clinical trial. Participants will: Take drug HPP737 or a placebo orally every day Visit the clinic regularly for checkups and tests throughout the study Have their psoriasis severity assessed using standardized scoring tools, including the Psoriasis Area and Severity Index (PASI), static Physician's Global Assessment (sPGA), and Body Surface Area (BSA) Eligible participants are adults aged 18 years and older with a confirmed diagnosis of chronic plaque psoriasis for at least 6 months and moderate-to-severe disease at screening.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (50)

Beijing Friendship Hospital, Capital Medical UniversityBeijing, China
Beijing Tongren Hospital, Capital Medical UniversityBeijing, China
Peking University People's HospitalBeijing, China
The First Affiliated Hospital of Bengbu Medical CollegeBengbu, China
Cangzhou People's HospitalCangzhou, China
The Second Hospital of Jilin UniversityChangchun, China
The Second Xiangya Hospital of Central South UniversityChangsha, China
The Third Xiangya Hospital of Central South UniversityChangsha, China
Xiangya Hospital, Central South UniversityChangsha, China
Affiliated Hospital of Chengde Medical CollegeChengde, China
Chengdu Second People's HospitalChengdu, China
Dongguan First People's HospitalDongguan, China

+ 38 more locations — full list on the registry record.

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