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Study identifier: NCT07707141 Synced from ClinicalTrials.gov · August 03, 2026
● Completed

Safety and Efficacy of HPP737 in Adult Patients With Plaque Psoriasis

Condition: Psoriasis  ·  Sponsor: Newsoara Biopharma Co., Ltd.

PhasePhase 2
Planned participants123
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if drug HPP737 works to treat moderate-to-severe plaque psoriasis in adults. It will also learn about the safety of drug HPP737. The main questions it aims to answer are: Does drug HPP737 improve psoriasis severity compared to placebo, as measured by the proportion of patients achieving at least a 75% improvement in the Psoriasis Area and Severity Index (PASI 75) at Day 85? What medical problems do participants have when taking drug HPP737? Researchers will compare drug HPP737 to a placebo (a look-alike substance that contains no drug) to see if drug HPP737 works to treat moderate-to-severe plaque psoriasis. Participants will: Take drug HPP737 or a placebo orally every day Visit the clinic regularly for checkups and tests throughout the study Have their psoriasis severity assessed using standardized scoring tools (PASI, Physician's Global Assessment (PGA), and Body Surface Area ( BSA)) This is a multicenter, randomized, double-blind, placebo-controlled Phase II clinical trial. Eligible participants are adults aged 18 to 70 years with chronic plaque psoriasis for at least 6 months and moderate-to-severe disease at screening.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (8)

Beijing Friendship Hospital, Capital Medical UniversityBeijing, China
Beijing Tsinghua Changgung HospitalBeijing, China
Sir Run Run Shaw Hospital, Zhejiang University School of MedicineHangzhou, China
Shandong Provincial Hospital for Skin Diseases, Shandong First Medical UniversityJinan, China
The First People's Hospital of LianyungangLianyungang, China
Hospital of Dermatology, Chinese Academy of Medical SciencesNanjing, China
Hong Kong University Shenzhen HospitalShenzhen, China
Wuxi No.2 People's HospitalWuxi, China

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