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Study identifier: NCT07686835 Synced from ClinicalTrials.gov · August 04, 2026
● Recruiting

Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma.

Condition: Melanoma (Skin) Stage IV · Melanoma (Skin Cancer) · Melanoma Metastatic  ·  Sponsor: Radboud University Medical Center

PhasePhase 2
Planned participants70
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Previous research has shown that a higher fiber intake may have a beneficial effect on the intestinal health and improve the effectiveness of immunotherapy, but this is not certain. The objective of this double-blinded randomized clinical trial is to analyze, whether increased dietary fiber intake by patients with metastatic melanoma will increase the relative amount of Bifidobacterium, which in turn stimulates immune cell activity and improves the response to immunotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Kalijn Bol, dr.  ·  +31 243618800  ·  Kalijn.Bol@radboudumc.nl

Isabel Ossekoppele, MS  ·  Isabel.Ossekoppele@radboudumc.nl

Always discuss trial participation with your own doctor first.

Locations (2)

Medical OncologyNijmegen, Gelderland, NetherlandsRecruiting
Universitair Medisch Centrum GroningenGroningen, Provincie Groningen, NetherlandsNot Yet Recruiting

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