INterest of the Negative Predictive Value of Integrons in the reduCtion of Large Broad-spectrum anTibiotics Consumption for Urinary Tract infectionS
Condition: Drug Resistance, Microbial · Biomarkers · Urinary Tract Infections (UTI's) · Sponsor: University Hospital, Limoges
About this study
Urinary tract infections (UTI), mainly driven by Gram-negative bacteria (GNB) are a frequent cause of hospitalization and the second cause of antibiotic prescription after lower respiratory tract infections. Integrons play a major role in the dissemination of antibiotic resistance among GNB. In the prospective INVICTUS project, whose ultimate objective is to reduce the use of large broad-spectrum antibiotics, our hypothesis is that, in adult patients with a non-severe UTI (qSOFA\<2) and a former documentation with a 3GC-resistant GNB in the previous 6 months, integrons search could reduce the empirical use of large broad-spectrum antibiotics.
This description comes directly from the study's public registry record.
Talk to the study team
Olivier BARRAUD, MD · 055505665 · olivier.barraud@chu-limoges.fr
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Locations (7)
| CHRU Tours, Hôpital Trousseau | Chambray-lès-Tours, France | — |
| Grenoble university hospital | La Tronche, France | — |
| Limoges university hospital | Limoges, France | — |
| Hopital lariboisière | Paris, France | — |
| Hôpital Saint Louis - APHP | Paris, France | — |
| Groupe Hospitalier Universitaire Bichat-Claude Bernard - APHP | Paris, France | — |
| CHU de Reims | Reims, France | — |
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Source record: clinicaltrials.gov/study/NCT07675018