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Study identifier: NCT07648173 Synced from ClinicalTrials.gov · August 04, 2026
● Recruiting

Hybrid HIIT-FES Cycling Program on Individuals With Spinal Cord Injury to Improve Health

Condition: Spinal Cord Injuries  ·  Sponsor: William Carey University

PhaseNA
Planned participants12
Who can joinAll sexes, 21 Years to 70 Years
Healthy volunteersNo

About this study

Project Summary/Abstract Obesity and metabolic syndrome (obesity, dyslipidemia, hyperglycemia, hypertension) are epidemic in the spinal cord injured (SCI) population. A recent study assessing the body composition and metabolic syndrome rates of 72 motor complete chronic SCI individuals revealed an obesity rate of over 90% and a metabolic syndrome rate of 60%. These results are significantly higher than in the general population. As such individuals with SCI typically have systemic inflammation and an accelerated trajectory towards cardiometabolic disease, and early mortality. Although the accelerated trajectory is multi-factorial, substantial evidence implicates sedentary behavior and low physical activity levels as significant contributing factors. Exercise strategies for individuals with SCI have included upper body arm crank exercise (ACE), functional electrical stimulation leg cycling exercise (FES-LCE), or a combination of the two (FES Hybrid Exercise). These modalities have yielded modest improvements in physical fitness and cardiometabolic risk profiles in individuals with SCI. FES-LCE reportedly increased lean-to-fat mass ratio, enhanced peripheral blood flow and vasoreactivity, and increased bone mass in the paralyzed legs. In addition, FES-LCE improves metabolic function as evidenced by increased glucose disposal. There is evidence that high-intensity interval training exercise can increase muscle mass and improve cardiovascular fitness with considerably less time c…

This description comes directly from the study's public registry record.

Talk to the study team

David R Dolbow, DPT, PhD  ·  601-318-6274  ·  ddolbow@wmcarey.edu

Always discuss trial participation with your own doctor first.

Locations (1)

William Carey UniversityHattiesburg, Mississippi, United StatesRecruiting

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