Condition: Periprosthetic Joint Infection (PJI) · Sponsor: Thomas Jefferson University
Patients with an infected knee replacement will receive their standard of care surgical treatment of the infection, with and without additional ultrasound microbubble treatment (randomly divided 50/50 in the active and control groups). Subjects in the active group will receive a local bolus injection of antibiotics and ultrasound-active microbubbles within 24 hours of their revision surgery. The fundamental hypothesis is that a decrease in re-infection rates of at least 24% can be achieved in the active group relative to controls.
This description comes directly from the study's public registry record.
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| Thomas Jefferson University/Rothman Institute | Philadelphia, Pennsylvania, United States | Recruiting |
| University of Pittsburgh Medical Center (UPMC) | Pittsburgh, Pennsylvania, United States | Not Yet Recruiting |
| UT Southwestern Medical Center | Dallas, Texas, United States | Not Yet Recruiting |
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