Condition: Chronic Coronary Syndrome · Sponsor: Seoul National University Hospital
Comparison of the incidence of major cardiovascular events between the combination of percutaneous intervention and optimal drug therapy and the optimal drug therapy alone in patients with chronic coronary syndrome. * Main RCT (Randomized Clinical Trial): Patients with chronic coronary syndrome enrolled in the study will be randomized in a 1:1 ratio to either 1) PCI(Percutaneous Coronary Intervention) plus optimal medical therapy or 2) optimal medical therapy alone, with clinical outcomes assessed during follow-up. (2,301 participants) * Nested RCT: An embedded randomized supplementary study was conducted on a subset (220 participants) of the total subjects. In patients who have decided to use beta-blockers for the control of angina, additional 1:1 randomization evaluates the efficacy of carvedilol sustained-release (SR) and immediate-release (IR) formulations. Both formulations are targeted for use up to the maximal tolerated dose, taking into account patient symptoms.
This description comes directly from the study's public registry record.
Jung-Kyu Han, MD, PhD · +82-2-2072-4870 · hpcrates@gmail.com
Always discuss trial participation with your own doctor first.
| Kangwon National University Hospital | Chuncheon, Gangwon-do, South Korea | — |
| GangNeung Asan Hospital | Gangneung, Gangwon-do, South Korea | — |
| Hallym University Medical Center | Anyang-si, Gyeonggi-do, South Korea | — |
| Bucheon Sejong Hospital | Bucheon-si, Gyeonggi-do, South Korea | — |
| Inje University Ilsan Paik Hospital | Goyang-si, Gyeonggi-do, South Korea | — |
| Samsung Changwon Medical Center | Changwon, Gyeongsangnam-do, South Korea | — |
| Inje University Haeundae Paik Hospital | Busan, South Korea | — |
| Pusan National University Hospital | Busan, South Korea | — |
| Kosin University Gospel Hospital | Busan, South Korea | — |
| Keimyung University Dongsan Hospital | Daegu, South Korea | — |
| Kyungpook National University Hospital | Daegu, South Korea | — |
| The Catholic University of Korea Daejeon St. Mary's Hospital | Daejeon, South Korea | — |
+ 8 more locations — full list on the registry record.
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