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Study identifier: NCT07571681 Synced from ClinicalTrials.gov · August 03, 2026
● Recruiting

Colchicine for Autoimmune and Subacute Thyroiditis

Condition: Hashimoto Thyroiditis · Subacute Thyroiditis · Thyroiditis  ·  Sponsor: Mansoura University

PhasePhase 2/Phase 3
Planned participants300
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Thyroiditis includes inflammatory thyroid disorders such as Hashimoto's thyroiditis and subacute thyroiditis. These conditions may cause thyroid pain, neck tenderness, elevated inflammatory markers, thyroid dysfunction, fatigue, and recurrence. Current management includes observation, symptomatic treatment, nonsteroidal anti-inflammatory drugs, and corticosteroids. Although corticosteroids may be effective, relapse after tapering and treatment-related adverse effects remain limitations. Colchicine is hypothesized to reduce inflammatory activity and may improve biochemical and clinical recovery. This study will evaluate the efficacy and safety of low-dose colchicine compared with corticosteroid therapy and supportive care in adults with autoimmune or subacute thyroiditis.

This description comes directly from the study's public registry record.

Talk to the study team

Amr A. El Sehrawy, MD, PhD, FRCPE  ·  +966503845019  ·  amrsehrawy@mans.edu.eg

Amro A. Elbaz, MD  ·  +201000191910  ·  dramrbaz@mans.edu.eg

Always discuss trial participation with your own doctor first.

Locations (2)

Mansoura UniversityAl Mansurah, Dakahlia Governorate, EgyptRecruiting
Saudi German HospitalJeddah, Mecca Region, Saudi ArabiaRecruiting

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