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Study identifier: NCT07571109 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

Condition: Obesity · Overweight · Obstructive Sleep Apnoea  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants300
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is being done to look at the efficacy and safety of NNC0487-0111 in participants with overweight or obesity, and obstructive sleep apnoea treated with positive airway pressure. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111, (the treatment being tested) or Placebo (a treatment that has no active medicine in it) and which treatment participants get is decided by chance.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (92)

Dignity Health, Mercy GilbertGilbert, Arizona, United StatesRecruiting
DM ClinicalBradenton, Florida, United StatesRecruiting
Essence MD ResearchNaples, Florida, United StatesRecruiting
Palm Beach Research CenterWest Palm Beach, Florida, United StatesRecruiting
NeuroTrials Research, Inc.Atlanta, Georgia, United StatesRecruiting
Physicians Research AssociatesLawrenceville, Georgia, United StatesRecruiting
Chicago Research Center, IncChicago, Illinois, United StatesRecruiting
Weil Cornell MedicineNew York, New York, United StatesRecruiting
Lillestol Research LLCFargo, North Dakota, United StatesRecruiting
CTI Clinical Research CenterCincinnati, Ohio, United StatesRecruiting
Clinical Research Associates of Central PA, LLCDuBois, Pennsylvania, United StatesNot Yet Recruiting
Bogan Sleep Consultants, LLCColumbia, South Carolina, United StatesRecruiting

+ 80 more locations — full list on the registry record.

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