EICHOR
● Recruiting
A Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of TQ05105 Tablets in Subjects With Intermediate/High-risk Myelofibrosis
Condition: Myelofibrosis · Sponsor: Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
About this study
This is an open-label, single-arm, multi-center phase II study consisting of two cohorts. Cohort 1 evaluates the pharmacokinetics (PK) of TQ05105 in myelofibrosis participants with normal, mild, or moderate renal impairment to guide dosing. Cohort 2 evaluates the efficacy and safety of TQ05105 in participants with intermediate/high-risk myelofibrosis who are refractory, relapsed, or intolerant to prior Janus kinase (JAK) inhibitor therapy.
This description comes directly from the study's public registry record.
Talk to the study team
Chunkang Chang, Doctor · 13764643870 · changchunkang7010@aliyun.com
Always discuss trial participation with your own doctor first.
Locations (24)
| The First Affiliated Hospital of University of Science and Technology of China | Hefei, Anhui, China | Recruiting |
| Fujian Medical University Union Hospital | Fuzhou, Fujian, China | Recruiting |
| Guangzhou First Municipal People's Hospital | Guangzhou, Guangdong, China | Recruiting |
| The First Affiliated Hospital of Guangxi Medical University | Nanning, Guangxi, China | Recruiting |
| Cangzhou People's Hospital rovince | Cangzhou, Hebei, China | Recruiting |
| Affiliated Hospital of Chengde Medical College | Chengde, Hebei, China | Recruiting |
| The Second Hospital of Hebei Medical University | Shijiazhuang, Hebei, China | Recruiting |
| Xingtai People's Hospital | Xingtai, Hebei, China | Recruiting |
| Henan Cancer Hospital | Zhengzhou, Henan, China | Recruiting |
| Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology | Wuhan, Hubei, China | Recruiting |
| Union Hospital Tongji College Huazhong University of Science and Technology | Wuhan, Hubei, China | Recruiting |
| Zhuzhou Central Hospital | Zhuzhou, Hunan, China | Recruiting |
+ 12 more locations — full list on the registry record.
Follow this study
Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.
We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07551427