Condition: Depression · Treatment Resistant Depression · Major Depressive Disorder · Sponsor: University of California, San Diego
Repetitive Transcranial Magnetic stimulation (rTMS) is an FDA-approved therapy for treatment resistant depression (TRD) that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region. But studies of rTMS alone show remission rates of \~30%. Additionally, rTMS has not been shown to improve cognitive functioning that may be an independent factor predicting treatment success. This study will develop a novel multimodal treatment, which combines intermittent theta burst stimulation (iTBS) - a type of rTMS with digital mindfulness training to engage brain plasticity, enhance cognition and alleviate depression symptoms in individuals with TRD.
This description comes directly from the study's public registry record.
Jyoti Mishra, PhD · 858-232-2855 · braine@ucsd.edu
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| UC San Diego Health Psychiatry | San Diego, California, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07512284