Simplified Exercise-based Risk Assessment in Lung Cancer
Condition: Lung Cancer (Diagnosis) · Lobectomy · Surgery Complications · Sponsor: Linkoeping University
About this study
Physiological evaluation is part of the preoperative risk estimation in patients with lung cancer, and it aids in the choice of treatment. Ventilatory efficiency during exercise has emerged as a strong predictor of major postoperative complications, so far determined during a maximal cardiopulmonary exercise test. However, this test is limited by its availability and high cost, due to the requirement of high-technological equipment and advanced expertise. The current project aims to evaluate a simplified and accessible method for risk evaluation before decision on treatment in lung cancer. It builds on recent advances in technology and knowledge and combines a simple, low-intensity cycling test with measurement of ventilatory efficiency (end-tidal carbon dioxide pressure) with a handheld monitor. In a prospective, multi-center design the investigators will include patients evaluated for suspected lung cancer. The main objective is to establish threshold values for end-tidal carbon dioxide associated with low respectively high risk of major complications in patients undergoing surgery. In addition, the study aims to determine if end-tidal carbon dioxide can predict severe side-effects during neoadjuvant or curatively aiming systemic therapy. The project is closely linked to clinical practice, and the results can be easily implemented due to the simple and cost-efficient methodology. the suggested simplified approach would also allow access to physiological evaluation where mor…
This description comes directly from the study's public registry record.
Talk to the study team
Kristofer Hedman, MD, PhD · +46 10 1033356 · kristofer.hedman@liu.se
Karolina Kristenson · karolina.kristenson@regionostergotland.se
Always discuss trial participation with your own doctor first.
Locations (5)
| Department of Pulmonology, Ryhov | Jönköping, Sweden | — |
| Department of Pulmonology, Kalmar County Hospital | Kalmar, Sweden | — |
| Department of Pulmonology, Blekinge Hospital | Karlskrona, Sweden | — |
| Department of Pulmonology, University Hospital | Linköping, Sweden | — |
| Department of Clinical Physiology | Lund, Sweden | — |
Follow this study
Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.
We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07506889