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Study identifier: NCT07462377 Synced from ClinicalTrials.gov · August 02, 2026
● Recruiting

A Phase 1 Study of EPI-326 in EGFR-mutant NSCLC and HNSCC

Condition: Epidermal Growth Factor · Epidermal Growth Factor Receptor · Epidermal Growth Factor Receptor Gene Mutation  ·  Sponsor: EpiBiologics

PhasePhase 1
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A phase 1 study to determine the safety, tolerability, PK, PD, and preliminary anti-tumor activity of ascending doses of EPI-326 administered to patients with locally advanced or metastatic HNSCC and to patients with any documented EGFR-mutant locally advanced or metastatic NSCLC.

This description comes directly from the study's public registry record.

Talk to the study team

EpiBiologics Clinical Trials  ·  650-955-7486  ·  clinicaltrials@epibiologics.com

Always discuss trial participation with your own doctor first.

Locations (6)

START Los AngelesLos Angeles, California, United StatesRecruiting
Astera Cancer CareEast Brunswick, New Jersey, United StatesRecruiting
START New York Long IslandLake Success, New York, United StatesRecruiting
Sarah Cannon and HCA Research InstituteNashville, Tennessee, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
South Texas Accelerated Research Therapeutics (START)San Antonio, Texas, United StatesRecruiting

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