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Study identifier: NCT07448038 Synced from ClinicalTrials.gov · August 02, 2026
● Recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacodynamics (PD), and Pharmacokinetics (PK) of Selnoflast in Reducing Vascular Inflammation in Participants With Atherosclerosis at Risk for Major Adverse Cardiac Events

Condition: Atherosclerosis  ·  Sponsor: Genentech, Inc.

PhasePhase 2
Planned participants162
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The main purpose of the study is to evaluate the efficacy of selnoflast compared with placebo in participants with atherosclerosis, at high-risk for major adverse cardiovascular event (MACE), who are currently on standard-of-care (SOC) therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: GC46102 https://forpatients.roche.com/  ·  888-662-6728  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. No email attachments https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (16)

Cardiovascular Research Foundation of Southern CaliforniaBeverly Hills, California, United StatesRecruiting
National Heart InstituteBeverly Hills, California, United StatesRecruiting
Amnova Clinical ResearchIrvine, California, United StatesRecruiting
Alliance Clinical West Hills (Focus Clinical Research)West Hills, California, United StatesRecruiting
Inpatient Research Clinic (Las Palmas Medical Research Center)Miami Lakes, Florida, United StatesRecruiting
Asha Clinical Research-Munster,LlcHammond, Indiana, United StatesRecruiting
Profound Research LLC at Cardiology and Vascular Associates - CAVABloomfield Hills, Michigan, United StatesRecruiting
Profound Research LLC at Millenium CardiologyFarmington Hills, Michigan, United StatesRecruiting
Ahmed Arif Medical Research Center (AA MRC LLC )Flint, Michigan, United StatesRecruiting
DiGiovanna Inst for Med Ed&ResNorth Massapequa, New York, United StatesRecruiting
Preferred Primary Care Physicians, IncPittsburgh, Pennsylvania, United StatesRecruiting
Southwest Family Medicine AssociatesDallas, Texas, United StatesRecruiting

+ 4 more locations — full list on the registry record.

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