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Study identifier: NCT07420283 Synced from ClinicalTrials.gov · August 03, 2026
● Recruiting

A Study of Brenipatide in Participants With Opioid Use Disorder

Condition: Opioid Use Disorder  ·  Sponsor: Eli Lilly and Company

PhasePhase 2
Planned participants465
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of this study is to see if brenipatide, when compared to placebo, is safe and effective for participants with opioid use disorder, when used with buprenorphine with or without naloxone. The maximum potential duration of study participation for a participant in Part A is approximately 144 weeks, maximum potential duration of study participation for a participant in Part B is approximately 116 weeks. The actual duration will vary for each participant depending on the time of enrollment and the overall rate of study enrollment.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  1-317-615-4559  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (58)

NoesisPharma - Phoenix - East Shea BoulevardPhoenix, Arizona, United StatesRecruiting
Pillar Clinical Research- Little RockLittle Rock, Arkansas, United StatesRecruiting
Woodland International Research GroupLittle Rock, Arkansas, United StatesRecruiting
Ark Clinical Research - Fountain ValleyFountain Valley, California, United StatesRecruiting
Center on Substance Use and Health (CSUH)San Francisco, California, United StatesRecruiting
UCSF Weill Institute for Neurosciences - Substance Use Disorders Clinic - Mission BaySan Francisco, California, United StatesRecruiting
Bradenton Research Center, Inc.Bradenton, Florida, United StatesRecruiting
K2 Medical Research - Daytona BeachDaytona Beach, Florida, United StatesRecruiting
NextPhase Research Florida - HollywoodHollywood, Florida, United StatesRecruiting
Accel Research Sites - Lakeland Clinical Research UnitLakeland, Florida, United StatesRecruiting
Life Arc Research Centers - MiamiMiami, Florida, United StatesRecruiting
Advanced Research for Health Improvement, LLCNaples, Florida, United StatesRecruiting

+ 46 more locations — full list on the registry record.

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