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Study identifier: NCT07418398 Synced from ClinicalTrials.gov · August 02, 2026
● Not Yet Recruiting

Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.

Condition: Spinal Cord Injury  ·  Sponsor: VA Office of Research and Development

PhaseNA
Planned participants24
Who can joinAll sexes, 21 Years to 60 Years
Healthy volunteersNo

About this study

Immobilization following spinal cord injury (SCI) results in muscle and bone loss below the level of injury, which ultimately predisposes to fracture at several sites throughout the legs and can lead to several medical complications that can devastate quality of life. There is a scarcity of research that has successfully implemented rehabilitation and/or exercise training interventions to preserve the musculoskeletal system during the acute phase SCI, or possibly reverse the muscle and bone loss that has already occurred in chronic SCI. This study will compare the effect of exoskeleton-assisted walking (EAW) training combined with transcutaneous spinal cord stimulation (tSCS) (EAW + active tSCS), to that of EAW + sham tSCS, on measures of muscle and bone health in a cohort of chronically injured motor incomplete SCI. A successful outcome would expand treatment options to improve musculoskeletal health over the lifetime.

This description comes directly from the study's public registry record.

Talk to the study team

Chris Cirnigliaro, MS  ·  (973) 731-3900  ·  christopher.cirnigliaro@va.gov

Christopher Cardozo, MD  ·  (718) 584-9000  ·  Christopher.Cardozo@va.gov

Always discuss trial participation with your own doctor first.

Locations (2)

Kessler FoundationWest Orange, New Jersey, United States
James J. Peters VA Medical Center, Bronx, NYThe Bronx, New York, United States

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