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Study identifier: NCT07407465 Synced from ClinicalTrials.gov · July 30, 2026
● Recruiting

Upfront Trastuzumab-Deruxtecan Plus Capecitabine and Bevacizumab for Patients With HER-2 Positive Metastatic Colorectal Cancer.

Condition: Colorectal Cancer · Colorectal Adenocarcinoma · Rectal Adenocarcinoma  ·  Sponsor: Gruppo Oncologico del Nord-Ovest

PhasePhase 2
Planned participants42
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this study is to evaluate the activity of first-line trastuzumab-deruxtecan, capecitabine and bevacizumab in terms of overall response rate for patients with HER-2 positive metastatic/locally advanced unresectable colorectal cancer

This description comes directly from the study's public registry record.

Talk to the study team

Filippo Pietrantonio, MD  ·  0039-3407683357  ·  filippo.pietrantonio@istitutotumori.mi.it

Federica M Palermo, Dr  ·  chimerastudy@istitutotumori.mi.it

Always discuss trial participation with your own doctor first.

Locations (28)

Hopital Prive Jean MermozLyon, FranceRecruiting
Hôpital La Timone - APHMMarseille, FranceRecruiting
Hopital Saint LouisParis, FranceRecruiting
Centre Hospitalier Universitaire ReimsReims, FranceRecruiting
Groupe Hospitalier Rance EmeraudeSt-Malo, FranceRecruiting
Charite UniversitaetsmedizinBerlin, GermanyRecruiting
Krankenhaus NordwestFrankfurt, GermanyRecruiting
Istituto Tumori Bari Giovanni Paolo IIBari, Bari, ItalyRecruiting
A.O.U CareggiFlorence, Firenze, ItalyRecruiting
Istituto Europeo Di Oncologia S.r.l.Milan, Italy, ItalyRecruiting
Azienda Unita Sanitaria Locale Della RomagnaRavenna, Italy, ItalyRecruiting
Humanitas Mirasole S.p.A.Rozzano, Italy, ItalyRecruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07407465