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Study identifier: NCT07352384 Synced from ClinicalTrials.gov · August 05, 2026
● Enrolling By Invitation

Evaluation of the Efficacy of Neuromodulation in the Control of Chronic Orofacial Pain

Condition: Orofacial Pain  ·  Sponsor: Egas Moniz - Cooperativa de Ensino Superior, CRL

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Chronic orofacial pain significantly affects patients' quality of life, compromising essential functions such as chewing and speech. Although conventional treatments are available, many patients do not achieve adequate and lasting relief. This project investigates the effectiveness of neuromodulation techniques, namely transcranial direct current stimulation (tDCS) and transcranial magnetic stimulation (TMS), as innovative therapeutic alternatives for the control of chronic orofacial pain. The study will be conducted in adult patients diagnosed with orofacial pain. Participants will be divided into two groups: one group will receive active neuromodulation (tDCS or TMS) and the other a sham treatment (placebo). Sessions will take place daily over two weeks. Assessments will include pain intensity, pain pressure threshold, masticatory function, and bite strength, in order to observe any functional changes. The group undergoing neuromodulation is expected to show a significant reduction in pain levels and improvements in quality of life compared to the placebo group. This study could support the adoption of neuromodulation as a complementary approach in the treatment of chronic orofacial pain, offering an effective and non-invasive alternative for patients who do not respond to conventional treatments.

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (1)

Egas Moniz School of Health and ScienceAlmada, Setúbal District, Portugal

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