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Study identifier: NCT07321912 Synced from ClinicalTrials.gov · August 02, 2026
● Recruiting

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

Condition: Osteosarcoma · Ewing Sarcoma  ·  Sponsor: Milton S. Hershey Medical Center

PhasePhase 2
Planned participants406
Who can joinAll sexes, 0 Years to 50 Years
Healthy volunteersNo

About this study

Ewing sarcoma (EWS) and osteosarcoma primarily affect adolescents and young adults. Common treatments include chemotherapy, surgery and radiation, however, there have been few recent advancements in the standard of care. By incorporating eflornithine (DFMO) as an additional therapy and/or maintenance therapy we hope to safely observe improved event-free survival and overall survival. There are 5 cohorts covered under this master protocol.

This description comes directly from the study's public registry record.

Talk to the study team

BCC Enroll  ·  7175310003  ·  BCCEnroll@pennstatehealth.psu.edu

Always discuss trial participation with your own doctor first.

Locations (2)

St. Joseph's Children's HospitalTampa, Florida, United StatesRecruiting
Penn State Milton S. Hershey Medical Center and Children's HospitalHershey, Pennsylvania, United StatesRecruiting

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