Condition: SCLC, Extensive Stage · Advanced Solid Tumors · Sponsor: Shanghai AB PharmaTech Ltd.
This study is a multicenter, open-label, multi-cohort investigation exploring the efficacy and safety of ABP1011T tablets in participants with specific target solid tumors, providing a foundation for subsequent clinical research. Based on safety and efficacy data from the prior Phase I/IIa clinical trial (Protocol Number: ABP1011T-I/II-01), priority enrollment is given to participants with advanced solid tumors including small cell lung cancer, esophageal cancer, cervical cancer, bladder cancer, and renal cell carcinoma (excluding osteosarcoma). Cohort A (Cohort A1, Cohort A2, Cohort A3) comprises the small cell lung cancer cohort: Participants must have failed at least two prior systemic therapies. Cohort B enrolls participants with other advanced solid tumors (excluding osteosarcoma). ABP1011T tablets are administered as continuous therapy in clinical studies, with a 21-day treatment cycle. Participants take one tablet orally once daily on an empty stomach (with water, avoiding food for at least 1 hour before and after each dose).
This description comes directly from the study's public registry record.
Haiping WANG, PhD · +86 21 5442 6122 · hpwang@abpharma.com
Always discuss trial participation with your own doctor first.
| The First Affiliated Hospital of Henan University of Science and Technology | Luoyang, Henan, China | Not Yet Recruiting |
| The First Affiliated Hospital of Nanyang Medical College | Nanyang, Henan, China | Not Yet Recruiting |
| The First Affiliated Hospital of Nanchang University | Nanchang, Jiangxi, China | Not Yet Recruiting |
| Liaocheng Second People's Hospital | Liaocheng, Shandong, China | Recruiting |
| Shanghai Pulmonary Hospital | Shanghai, Shanghai Municipality, China | Not Yet Recruiting |
| Shanxi Bethune Hospital | Taiyuan, Shanxi, China | Not Yet Recruiting |
| Neijiang First People's Hospital | Neijiang, Sichuan, China | Recruiting |
| Shanghai East Hospital | Shanghai, China | Recruiting |
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