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Study identifier: NCT07321574 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

A Study Evaluating the Efficacy and Safety of ABP1011T Tablets in Patients With Advanced Solid Tumors

Condition: SCLC, Extensive Stage · Advanced Solid Tumors  ·  Sponsor: Shanghai AB PharmaTech Ltd.

PhasePhase 2
Planned participants110
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is a multicenter, open-label, multi-cohort investigation exploring the efficacy and safety of ABP1011T tablets in participants with specific target solid tumors, providing a foundation for subsequent clinical research. Based on safety and efficacy data from the prior Phase I/IIa clinical trial (Protocol Number: ABP1011T-I/II-01), priority enrollment is given to participants with advanced solid tumors including small cell lung cancer, esophageal cancer, cervical cancer, bladder cancer, and renal cell carcinoma (excluding osteosarcoma). Cohort A (Cohort A1, Cohort A2, Cohort A3) comprises the small cell lung cancer cohort: Participants must have failed at least two prior systemic therapies. Cohort B enrolls participants with other advanced solid tumors (excluding osteosarcoma). ABP1011T tablets are administered as continuous therapy in clinical studies, with a 21-day treatment cycle. Participants take one tablet orally once daily on an empty stomach (with water, avoiding food for at least 1 hour before and after each dose).

This description comes directly from the study's public registry record.

Talk to the study team

Haiping WANG, PhD  ·  +86 21 5442 6122  ·  hpwang@abpharma.com

Always discuss trial participation with your own doctor first.

Locations (8)

The First Affiliated Hospital of Henan University of Science and TechnologyLuoyang, Henan, ChinaNot Yet Recruiting
The First Affiliated Hospital of Nanyang Medical CollegeNanyang, Henan, ChinaNot Yet Recruiting
The First Affiliated Hospital of Nanchang UniversityNanchang, Jiangxi, ChinaNot Yet Recruiting
Liaocheng Second People's HospitalLiaocheng, Shandong, ChinaRecruiting
Shanghai Pulmonary HospitalShanghai, Shanghai Municipality, ChinaNot Yet Recruiting
Shanxi Bethune HospitalTaiyuan, Shanxi, ChinaNot Yet Recruiting
Neijiang First People's HospitalNeijiang, Sichuan, ChinaRecruiting
Shanghai East HospitalShanghai, ChinaRecruiting

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