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Study identifier: NCT07287150 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

Condition: Metastatic Castration-Resistant Prostate Cancer  ·  Sponsor: Hoffmann-La Roche

PhasePhase 2
Planned participants100
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study will evaluate the efficacy and safety of the combination of inavolisib plus enzalutamide compared with physician's choice of alternative androgen receptor pathway inhibitor (ARPi) or docetaxel in biomarker-selected participants with metastatic castrate-resistant prostate cancer (mCRPC) who have received one prior second-generation ARPi.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: CO45813 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. and Canada)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (47)

VA West Los Angeles Medical Center - (CRS) - NAVREF - PPDSLos Angeles, California, United StatesRecruiting
UCSFSan Francisco, California, United StatesRecruiting
Holden Comprehensive Cancer CenterIowa City, Iowa, United StatesRecruiting
Montefiore Einstein Cancer CenterThe Bronx, New York, United StatesRecruiting
Lifespan Cancer InstituteProvidence, Rhode Island, United StatesRecruiting
Carolina Urologic Research CenterMyrtle Beach, South Carolina, United StatesRecruiting
Royal North Shore Hospital-Pacific HwySt Leonards, New South Wales, AustraliaRecruiting
Sunshine Coast University HospitalBirtinya, Queensland, AustraliaRecruiting
Royal Brisbane & Womens HospitalHerston, Queensland, AustraliaRecruiting
Box Hill HospitalBox Hill, Victoria, AustraliaRecruiting
Irmandade Da Santa Casa de Misericordia de Porto AlegrePorto Alegre, Rio Grande do Sul, BrazilRecruiting
CEPHO - Centro de Estudos e Pesquisas em Hematologia e OncologiaSanto André, São Paulo, BrazilRecruiting

+ 35 more locations — full list on the registry record.

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