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Study identifier: NCT07228403 Synced from ClinicalTrials.gov · August 04, 2026
● Active Not Recruiting

Efficacy and Safety Evaluation of Glepaglutide in Treatment of Short Bowel Syndrome

Condition: Short Bowel Syndrome (SBS)  ·  Sponsor: Zealand Pharma

PhasePhase 3
Planned participants28
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to understand the safety and efficacy of twice weekly glepaglutide 10 mg in adult patients with short bowel syndrome (SBS), who were previously enrolled in the EASE SBS 2 or EASE SBS 3 trials. Participants currently on these trials will be able to continue their glepaglutide treatment by enrolling in this EASE SBS 6 extension trial. The trial includes a 24-month treatment period, followed by a 4-week safety follow-up period. Participants will attend trial visits, where they may undergo heart tests (electrocardiogram (ECG)), vital sign checks, colonoscopies, blood and urine tests, and physical exams.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (16)

Mayo Clinic - PPDSRochester, Minnesota, United States
Lied Transplant Center at Nebraska Medical CenterOmaha, Nebraska, United States
Cleveland Clinic-9500 Euclid AveCleveland, Ohio, United States
Vanderbilt University Medical Center-Tennesse-1211 21st Ave SNashville, Tennessee, United States
UZ Leuven - PPDSLeuven, Belgium
LHSC - University HospitalLondon, Ontario, Canada
AP-HP - Hôpital BeaujonClichy, Hauts-de-Seine, France
Universitätsklinikum FrankfurtFrankfurt am Main, Hesse, Germany
Universitätsmedizin RostockRostock, Mecklenburg-Vorpommern, Germany
Universitätsklinikum BonnBonn, North Rhine-Westphalia, Germany
Charité - Universitätsmedizin BerlinBerlin, State of Berlin, Germany
Asklepios Klinik St. GeorgHamburg, Germany

+ 4 more locations — full list on the registry record.

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