Condition: Carcinoma, Non-Small-Cell Lung · Sponsor: Janssen Research & Development, LLC
The main purpose of this study is to find out the most suitable dose (recommended phase 2 combination dose \[RP2CD\]) of amivantamab and olomorasib combination therapy and to assess how well the combination slows down or prevents the growth of tumors in participants with KRAS G12C mutant metastatic non-small cell lung cancer (NSCLC: the most common type of lung cancer; metastatic: has spread to other parts of the body; KRAS G12C mutant: mutation \[change\] in the kirsten rat sarcoma viral oncogene homolog \[KRAS\] gene in tumor cells in which glycine \[G\] at position 12 is replaced with cystine \[C\]).
This description comes directly from the study's public registry record.
Study Contact · 844-434-4210 · Participate-In-This-Study1@its.jnj.com
Always discuss trial participation with your own doctor first.
| New York University Langone Medical Center | New York, New York, United States | Recruiting |
| Oncology Consultants Cancer Center | Houston, Texas, United States | Suspended |
| Virginia Cancer Specialists | Fairfax, Virginia, United States | Recruiting |
| Princess Margaret Hospital | Toronto, Ontario, Canada | Recruiting |
| The First Affiliated Hospital Sun Yat sen University | Guangzhou, China | Recruiting |
| Harbin medical university cancer hospital | Harbin, China | Recruiting |
| Shanghai East Hospital | Shanghai, China | Recruiting |
| Severance Hospital Yonsei University Health System | Seoul, South Korea | Recruiting |
| Asan Medical Center | Seoul, South Korea | Recruiting |
| Samsung Medical Center | Seoul, South Korea | Recruiting |
| Ankara Universitesi Hastaneleri Tibbi Farmakoloji Anabilim Dali Faz 1 Klinik Arastirma Merkezi | Ankara, Turkey (Türkiye) | Recruiting |
| Ankara Bilkent Sehir Hastanesi | Çankaya, Turkey (Türkiye) | Recruiting |
+ 1 more locations — full list on the registry record.
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