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Study identifier: NCT07225829 Synced from ClinicalTrials.gov · August 03, 2026
● Active Not Recruiting

A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis

Condition: Knee Osteoarthritis · Synovitis of Knee  ·  Sponsor: 4Moving Biotech

PhasePhase 2
Planned participants129
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

This phase 2a trial is an international, multicenter, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of one single intra-articular (IA) injection of 4P004 or placebo in: * patients between 40 and 80 years of age, * with synovitis and grade 2 to 4 osteoarthritis (OA) of the knee according to Kellgren and Lawrence (KL) classification.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (22)

Tucson Orthopaedic InstituteTucson, Arizona, United States
Northwestern University Feinberg School of MedicineChicago, Illinois, United States
Skylight Health Research BurlingtonBurlington, Massachusetts, United States
Durham Bone and Joint SpecialistsAjax, Canada
SJHC London Rheumatology CentreLondon, Canada
G.R.M.O. (Groupe de recherche en maladies osseuses) IncQuébec, Canada
Parker Institute Bispebjerg, Frederiksberg HospitalFrederiksberg, Denmark
Sanos Clinic HerlevHerlev, Denmark
CHU MontpellierMontpellier, France
ChU de NiceNice, France
Hôpital CochinParis, France
Hôpital LariboisièreParis, France

+ 10 more locations — full list on the registry record.

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