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Study identifier: NCT07215182 Synced from ClinicalTrials.gov · August 04, 2026
● Recruiting

[68Ga]Ga-FAPI Total Body PET/CT for Better and Faster Imaging in Cancer

Condition: Malignant Melanoma Stage IV  ·  Sponsor: Barbara Malene Fischer

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to investigate the use of the tracer \[68Ga\]Ga-FAPI-46 for PET/CT-imaging in response evaluation of patients with advanced stage malignant melanoma treated with immune checkpoint inhibitor therapy (ICT). The main question it aims to answer is: • Can \[68Ga\]Ga-FAPI-46 PET/CT improve response evaluation in patients suffering from advanced stage malignant melanoma treated with ICT and potentially serve as a biomarker. Researchers will compare findings on the experimental \[68Ga\]Ga-FAPI-46 PET/CT with findings on standard imaging (\[18F\]FDG PET/CT). Participants will undergo: * Two \[68Ga\]Ga-FAPI-46 PET/CT scans: one before treatment initiation with ICT and one after three months. * Two blood samples * Passive follow-up 6 months after the last scan \[68Ga\]Ga-FAPI-46 PET/CT

This description comes directly from the study's public registry record.

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Locations (2)

Herlev UniversityhospitalHerlev, Capital Region, DenmarkRecruiting
RigshospitaletCopenhagen, Ca, DenmarkRecruiting

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