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Study identifier: NCT07214727 Synced from ClinicalTrials.gov · August 04, 2026
● Recruiting

A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease

Condition: Alzheimer's Disease  ·  Sponsor: Alnylam Pharmaceuticals

PhasePhase 1
Planned participants50
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersNo

About this study

The purpose of this study is to: * Evaluate the safety and tolerability of intrathecal (IT) ALN-5288 in patients with Alzheimer's Disease (AD) * Evaluate the pharmacodynamic (PD) and pharmacokinetic (PK) effects of ALN-5288 after dose administration

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trial Information Line  ·  1-877-ALNYLAM  ·  clinicaltrials@alnylam.com

Clinical Trial Information Line  ·  1-877-256-9526  ·  clinicaltrials@alnylam.com

Always discuss trial participation with your own doctor first.

Locations (13)

Clinical Trial SiteMontreal, CanadaRecruiting
Clinical Trial SiteOttawa, CanadaRecruiting
Clinical Trial SiteToronto, CanadaRecruiting
Clinical Trial SiteToronto, CanadaNot Yet Recruiting
Clinical Trial Site's-Hertogenbosch, NetherlandsRecruiting
Clinical Trial SiteAmsterdam, NetherlandsNot Yet Recruiting
Clinical Trial SiteBarcelona, SpainNot Yet Recruiting
Clinical Trial SiteMadrid, SpainRecruiting
Clinical Trial SiteSant Cugat del Vallès, SpainNot Yet Recruiting
Clinical Trial SiteGlasgow, United KingdomRecruiting
Clinical Trial SiteLondon, United KingdomRecruiting
Clinical Trial SiteSheffield, United KingdomRecruiting

+ 1 more locations — full list on the registry record.

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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07214727