EichorEICHOR
Study identifier: NCT07197307 Synced from ClinicalTrials.gov · August 03, 2026
● Recruiting

Combining Loncastuximab Tesirine and Epcoritamab in Relapsed/Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Condition: Aggressive Diffuse Large B-cell Lymphoma · High-grade B-cell Lymphoma (HGBL) · Follicular Lymphoma (FL) Grade 3B  ·  Sponsor: Universität Münster

PhasePhase 2
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase II study designed to evaluate the toxicity and efficacy of the combination of loncastuximab tesirine and epcoritamab in patients with relapsed/refractory aggressive B-cell lymphoma. Chimeric antigen receptor (CAR)-T cell naive patients who have failed first-line therapy and patients who have received CAR-T cells as second-line therapy and experienced CAR-T failure will be eligible for inclusion.

This description comes directly from the study's public registry record.

Talk to the study team

Georg Lenz, Prof.  ·  +492518347587  ·  lenzsekr@ukmuenster.de

Always discuss trial participation with your own doctor first.

Locations (34)

Universitaetsklinikum AachenAachen, GermanyRecruiting
Universitaetsklinikum AugsburgAugsburg, GermanyRecruiting
Vivantes Netzwerk fuer GesundheitBerlin, GermanyRecruiting
Charite Universitaetsmedizin BerlinBerlin, GermanyRecruiting
HELIOS Klinikum Berlin-BuchBerlin, GermanyRecruiting
Evangelisches Klinikum BethelBielefeld, GermanyRecruiting
Klinikum ChemnitzChemnitz, GermanyRecruiting
Universitaetsklinikum DuesseldorfDüsseldorf, GermanyRecruiting
Universitaetsklinikum ErlangenErlangen, GermanyRecruiting
Universitaetsklinikum EssenEssen, GermanyNot Yet Recruiting
Universitaetsklinikum FrankfurtFrankfurt, GermanyRecruiting
Medical Center - University Of FreiburgFreiburg im Breisgau, GermanyRecruiting

+ 22 more locations — full list on the registry record.

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