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Study identifier: NCT07166094 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer

Condition: Endometrial Cancer · Recurrent or Progressive Endometrial Cancer  ·  Sponsor: Genmab

PhasePhase 3
Planned participants660
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to compare how well Rina-S (GEN1184) works compared to treatment of physician's choice (paclitaxel or doxorubicin) that are considered standard medical care for the treatment of recurrent or progressive endometrial cancer (EC) following prior therapy. There is an equal (50:50) chance of getting either Rina-S or a chemotherapy agent as treatment in this study. The study duration will be approximately 3 years. The treatment duration will be different for every participant, but an average of 4 to 6 months is expected. All participants will receive active drug; no one will be given placebo. Participation in the study will require visits to the study site(s).

This description comes directly from the study's public registry record.

Talk to the study team

Genmab Trial Information  ·  +4570202728  ·  clinicaltrials@genmab.com

Always discuss trial participation with your own doctor first.

Locations (147)

USAH Mitchell Cancer InstMobile, Alabama, United StatesRecruiting
HonorHealth Research InstPhoenix, Arizona, United StatesRecruiting
Kaiser Permanente SoCalIrvine, California, United StatesRecruiting
Norwalk HospitalDanbury, Connecticut, United StatesRecruiting
Norwalk HospitalNorwalk, Connecticut, United StatesRecruiting
MedStar Washington HospitalWashington D.C., District of Columbia, United StatesRecruiting
SMH - Sarasota - Main CampusSarasota, Florida, United StatesRecruiting
Women's Care - 9th AveSt. Petersburg, Florida, United StatesRecruiting
Women's Care - Armenia AveTampa, Florida, United StatesRecruiting
Emory Winship Cancer Inst.Atlanta, Georgia, United StatesRecruiting
Emory Winship Cancer Inst.Atlanta, Georgia, United StatesRecruiting
Northside Hospital AtlantaAtlanta, Georgia, United StatesRecruiting

+ 135 more locations — full list on the registry record.

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