● Recruiting

Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases

Condition: Leptomeningeal Metastasis · Sponsor: Plus Therapeutics

PhasePhase 1

Planned participants24

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

This is an open-label, multicenter, Phase 1 study to determine the safety and efficacy of multiple doses at defined intervals of rhenium (186Re) obisbemeda (rhenium-186 nanoliposome, 186RNL) administered via intraventricular catheter for any primary solid tumor cancer with leptomeningeal metastases to identify an MTD/MFD for a given dose, interval duration, and number of doses.

This description comes directly from the study's public registry record.

Talk to the study team

Rachael Hershey · 1(210)791-8723 · patients@respect-trials.com

Andrew Brenner, M.D.,Ph.D · 1(210)791-8723 · patients@respect-trials.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Cancer Therapy and Research Center at UTHSCSA

San Antonio, Texas, United States

Recruiting

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Source record: clinicaltrials.gov/study/NCT07098806