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Study identifier: NCT07097935 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of HS-10516 Combination Therapy in Patients With Advanced Renal Cell Carcinoma

Condition: Advanced Clear Cell Renal Cell Carcinoma  ·  Sponsor: Jiangsu Hansoh Pharmaceutical Co., Ltd.

PhasePhase 1/Phase 2
Planned participants104
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, open-label, Phase Ib/II clinical study evaluating the safety, efficacy, tolerability, and pharmacokinetic/pharmacodynamic (PK/PD) profiles of HS-10516 in combination with lenvatinib in patients with advanced clear cell renal cell carcinoma (ccRCC) who have progressed after receiving at least one prior line of systemic therapy. The study comprises two distinct phases: a dose exploration phase and a proof-of-concept phase.

This description comes directly from the study's public registry record.

Talk to the study team

Jun Guo  ·  010-88196358  ·  guoj307@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Cancer HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07097935