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Study identifier: NCT07040319 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of the Pharmacokinetics and Safety of Glecaprevir/Pibrentasvir Initiated in Pregnancy in Women With Hepatitis C With and Without HIV

Condition: Hepatitis C  ·  Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

PhasePhase 1/Phase 2
Planned participants30
Who can joinFemale, 16 Years to 45 Years
Healthy volunteersNo

About this study

This is a Phase I/II, multi-site, open-label, single arm study to describe the pharmacokinetics (PK) and safety of glecaprevir/pibrentasvir (GLE/PIB) initiated during pregnancy in women with hepatitis C virus (HCV) infection (acute or chronic) with or without HIV and to evaluate safety for their infants through 10 weeks postpartum.

This description comes directly from the study's public registry record.

Talk to the study team

IMPAACT ClinicalTrials.gov Coordinator  ·  impaact.ctgov@fstrf.org

Katie McCarthy  ·  919-321-3326  ·  kmccarthy@fhi360.org

Always discuss trial participation with your own doctor first.

Locations (10)

USC LALos Angeles, California, United StatesRecruiting
David Geffen School of Medicine at UCLALos Angeles, California, United StatesNot Yet Recruiting
University of Colorado DenverAurora, Colorado, United StatesRecruiting
Univ. of Florida JacksonvilleJacksonville, Florida, United StatesRecruiting
Lurie Children's Hospital of ChicagoChicago, Illinois, United StatesRecruiting
Johns Hopkins University BaltimoreBaltimore, Maryland, United StatesRecruiting
SUNY Stony BrookStony Brook, New York, United StatesRecruiting
Bronx-Lebanon Hospital CenterThe Bronx, New York, United StatesRecruiting
Jacobi Medical CenterThe Bronx, New York, United StatesNot Yet Recruiting
Baylor College of Medicine//Texas Children's HospitalHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07040319