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Study identifier: NCT07037758 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

Condition: Extensive Stage Small Cell Lung Cancer  ·  Sponsor: Amgen

PhasePhase 1
Planned participants380
Who can joinAll sexes, 18 Years to 90 Years
Healthy volunteersNo

About this study

The primary objective for dose exploration and dose expansion is to evaluate the safety and tolerability of tarlatamab in combination with AB248. The primary objective for dose exploration only is to determine the recommended dose for expansion and/or maximum tolerated combination dose (MTCD) of AB248 in combination with tarlatamab.

This description comes directly from the study's public registry record.

Talk to the study team

Amgen Call Center  ·  866-572-6436  ·  medinfo@amgen.com

Always discuss trial participation with your own doctor first.

Locations (19)

Banner MD Anderson Cancer CenterGilbert, Arizona, United StatesRecruiting
University of Southern California, Norris Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting
Moffitt Cancer CenterTampa, Florida, United StatesRecruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Norton Cancer Institute - DowntownLouisville, Kentucky, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Siteman Cancer CenterSt Louis, Missouri, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Sidney Kimmel Cancer CenterPhiladelphia, Pennsylvania, United StatesRecruiting
Allegheny General HospitalPittsburgh, Pennsylvania, United StatesRecruiting
Avera Cancer InstituteSioux Falls, South Dakota, United StatesRecruiting
Baptist Cancer CenterMemphis, Tennessee, United StatesRecruiting

+ 7 more locations — full list on the registry record.

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