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Study identifier: NCT07019844 Synced from ClinicalTrials.gov · August 02, 2026
● Recruiting

PSMA PET for the Staging and Management of Hepatocellular Carcinoma

Condition: Hepatocellular Carcinoma (HCC)  ·  Sponsor: VA Office of Research and Development

PhaseN/A
Planned participants90
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This prospective, single-center study evaluates the clinical utility of F18-Piflufolastat (PSMA) PET/CT when added to conventional cross-sectional imaging for patients with suspected or confirmed hepatocellular carcinoma (HCC). The study aims to determine whether PSMA PET/CT improves diagnostic accuracy for indeterminate liver lesions (LI-RADS 3 and 4), enhances staging precision in treatment-naïve patients, and provides more accurate assessment of treatment response in patients undergoing locoregional therapy (LRT). The goal is to assess how PSMA PET/CT may impact clinical decision-making, staging, and management of HCC across multiple stages of disease.

This description comes directly from the study's public registry record.

Talk to the study team

Binu V John, MD MPH  ·  (305) 575-7000  ·  binu.john@va.gov

Flavia R Carneiro, PhD  ·  (305) 575-7762  ·  flavia.carneiro@va.gov

Always discuss trial participation with your own doctor first.

Locations (2)

VA Greater Los Angeles Healthcare System, West Los Angeles, CAWest Los Angeles, California, United StatesRecruiting
Miami VA Healthcare System, Miami, FLMiami, Florida, United StatesRecruiting

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