Study identifier: NCT07000123 Synced from ClinicalTrials.gov · August 05, 2026
● Active Not Recruiting

A Phase III Study to Assess the Effect of AZD0780 on LDL-C in Patients With Clinical ASCVD or at Risk for a First ASCVD Event

Condition: Cardiovascular Disease  ·  Sponsor: AstraZeneca

PhasePhase 3
Planned participants3103
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a study to evaluate the efficacy and safety of AZD0780 in adults with clinical ASCVD or who are at risk for a first ASCVD event and who have elevated LDL-C. AZD0780 is a small molecule that reduces the amount of LDL-C in the blood. Placebo will be used for comparison, and neither the participants nor the Investigators will know who is receiving the AZD0780 medication and who is receiving the placebo until the end of study. The total length of the study for an individual participant will be up to approximately 56 weeks, including a screening period of up to 14 days, treatment with AZD0780 or placebo for 52 weeks, and a safety follow-up period of 10 days.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (405)

Research SiteHuntsville, Alabama, United States
Research SiteIrondale, Alabama, United States
Research SiteMobile, Alabama, United States
Research SiteGilbert, Arizona, United States
Research SitePhoenix, Arizona, United States
Research SiteSun City West, Arizona, United States
Research SiteGarden Grove, California, United States
Research SiteGardena, California, United States
Research SiteLancaster, California, United States
Research SiteLincoln, California, United States
Research SiteSan Diego, California, United States
Research SiteSan Diego, California, United States

+ 393 more locations — full list on the registry record.

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