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Study identifier: NCT06993792 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Master Protocol for Orforglipron (LY3502970) in Participants With Obesity or Overweight With and Without Type 2 Diabetes

Condition: Obesity · Overweight · Type 2 Diabetes  ·  Sponsor: Eli Lilly and Company

PhasePhase 3
Planned participants1400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this Master Protocol is to support two studies to see how well and how safely orforglipron works compared to placebo in participants who have obesity or overweight with or without type 2 diabetes. Participants will be screened for about 4 weeks, after which they will enroll into either J2A-MC-GZP1, NCT06972459 (do not have type 2 diabetes) or J2A-MC-GZP2, NCT06972472 (have type 2 diabetes).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (80)

Clinical Research Institute of Arizona (CRI) - Sun City WestSun City West, Arizona, United States
Novak Clinical Research - Tucson - North La Cholla BoulevardTucson, Arizona, United States
Norcal Endocrinology & Internal MedicineSan Ramon, California, United States
Southern California Clinical ResearchSanta Ana, California, United States
Care Access - Thousand OaksThousand Oaks, California, United States
Accel Research Sites - DeLand Clinical Research UnitDeLand, Florida, United States
Innovation Medical Research Center - Fort LauderdaleFort Lauderdale, Florida, United States
Indago Research & Health Center, IncHialeah, Florida, United States
Encore Medical ResearchHollywood, Florida, United States
West Orange Endocrinology P.A.Ocoee, Florida, United States
Care Access - TampaTampa, Florida, United States
Conquest ResearchWinter Park, Florida, United States

+ 68 more locations — full list on the registry record.

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