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Study identifier: NCT06938321 Synced from ClinicalTrials.gov · August 05, 2026
● Recruiting

A Study of AK130 in Combination With AK112 for the Treatment of Advanced Biliary Tract Cancer

Condition: Biliary Tract Cancer  ·  Sponsor: Akeso

PhasePhase 1/Phase 2
Planned participants135
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

There're 2 parts in this interventional study: 1. The goal of phase Ib trial is to evaluate the safety and tolerability of AK130 in combination with AK112 therapy for the purpose of observing the incidence of dose limit toxicity (DLT) as well as the confirmation of maximum tolerable dose (MTD) in the treatment of advanced biliary tract cancer (BTC), so as to determine the recommended phase 2 dose (RP2D) in the second part of the trial. 2. The goal of phase II trial is to evaluate the safety and efficacy of AK112 in combination with AK130 therapy or monotherapy in the treatment of advanced BTC.

This description comes directly from the study's public registry record.

Talk to the study team

Wenting Li  ·  18116403289  ·  wenting01.li@akesobio.com

Always discuss trial participation with your own doctor first.

Locations (1)

Peking Union Medical College Hospital, Chinese Academy of Medical SciencesBeijing, Beijing Municipality, ChinaRecruiting

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