Condition: Intoxication by Drug · Sponsor: Universitair Ziekenhuis Brussel
In this trial the investigators assess the effectiveness of applying a hemadsorber (cytosorb®) in removing benzodiazepines or tricyclic antidepressants in intoxicated patients admitted to ICU with prolonged impaired consciousness. This is a one arm interventional investigation where a hemadsorption filter is applied in patients fulfilling inclusion criteria 8 hours after admission. Plasma titer of the neurodepressing drug will be collected sequentially both before and after start of hemadsorption to evaluate the speed of drug elimination before and after application of a hemadsorption filter. Pre- and post filter titers will be obtained to evaluate adsorbability and to evaluate time to saturation of the filter.
This description comes directly from the study's public registry record.
Marie-Claire vanmalderen, Study coordinator · 0032 24 76 31 10 · Marieclaire.vanmalderen@uzbrussel.be
Merel Stevens, Study coordinator · 0032 24 76 30 96 · Merel.stevens@uzbrussel.be
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| Universitair Ziekenhuis Brussel | Brussels, Brussels Capital, Belgium | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06922786