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Study identifier: NCT06812923 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

TACS on High-inflammatory and Refractory Depression

Condition: Treatment Resistant Depression (TRD) · Inflammation  ·  Sponsor: Tianjin Anding Hospital

PhaseNA
Planned participants52
Who can joinAll sexes, 18 Years to 55 Years
Healthy volunteersNo

About this study

This study is a randomized controlled trial with a duration of 12 weeks (4 weeks of intervention + 8 weeks of follow-up). The participants are patients with treatment-resistant depression (TRD) and high inflammatory activity (n=52). The study aims to clarify the effectiveness of 15mA, 77.5Hz transcranial alternating current stimulation (tACS) in treating TRD with high inflammatory activity by comparing the changes in depressive symptoms and biological markers after active tACS stimulation versus sham stimulation. Additionally, the study seeks to explore potential underlying mechanisms of action.

This description comes directly from the study's public registry record.

Talk to the study team

Chenghao Yang, PhD  ·  0086-022-88188299  ·  yangchh@tjmhc.com

Always discuss trial participation with your own doctor first.

Locations (1)

The 20th ward of general psychiatric departmentTianjin, Tianjin Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06812923