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Study identifier: NCT06808230 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cocoa Extract for Migraine Trial

Condition: Migraine  ·  Sponsor: Brigham and Women's Hospital

PhaseNA
Planned participants114
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to assess the feasibility of recruitment and adherence to a high-dose cocoa extract supplement in individuals diagnosed with episodic migraine. The main questions it aims to answer are: * Will we be able to enroll 114 participants during the recruitment period? * Will participants take study pills daily during the pill-taking period? Researchers will compare two doses of cocoa extract to placebo to determine the acceptability of higher doses of cocoa extract supplementation in this patient population. Participants will be asked to: * Provide two urine samples * Complete daily questionnaires * Take four study pills a day for 12 weeks

This description comes directly from the study's public registry record.

Talk to the study team

Pamela M Rist, ScD  ·  877-517-2555  ·  bwhcoral@mgb.org

Always discuss trial participation with your own doctor first.

Locations (1)

Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06808230