Endometrial Carcinoma: Comparison of Surgical Approaches (Laparoscopy vs Laparotomy)
Condition: Endometrial Carcinoma · Sponsor: Azienda USL Reggio Emilia - IRCCS
About this study
Since the publication of the LAP2 study, a prospective randomized trial, laparoscopy has been considered the gold standard for treating patients with early-stage endometrial cancer (EC). However, no prospective randomized trials have been published reporting comparable data in patients with EC at high risk of recurrence (advanced stages or non-endometrioid histology). Nonetheless, some retrospective studies and a systematic review of the literature have demonstrated that minimally invasive surgery achieves better perioperative outcomes than laparotomy without compromising survival in patients with EC at high risk of recurrence. The aim of this multicenter retrospective observational study is to evaluate the safety of minimally invasive surgery in treating EC at low, intermediate, and high risk of recurrence according to the ESMO-ESGO classification, based on cases treated in hospitals within the Emilia Romagna region. Specifically, we aim to assess the effects of a minimally invasive surgical approach compared to laparotomy in terms of: 1. Perioperative and postoperative complications: including the need for transfusions during and/or after surgery, duration of surgery, fever exceeding 38°C for more than 48 hours, and length of hospitalization. 2. Long-term oncological outcomes: including overall survival, disease-free survival, recurrence rates, recurrence sites, and time to recurrence. This comparison will include patients treated for both endometrioid and non-endometrio…
This description comes directly from the study's public registry record.
Talk to the study team
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Locations (8)
| Azienda USL IRCCS di Reggio Emilia | Reggio Emilia, RE, Italy | — |
| IRCCS - AOU Bologna | Bologna, Italy | — |
| Policlinico Sant'Orsola - Malpighi | Bologna, Italy | — |
| Azienda Ospedaliera- Universitaria Arcispedale Sant'Anna Ferrara | Ferrara, Italy | — |
| Ospedale Morgagni - Pierantoni | Forlì, Italy | — |
| Policlinico di Modena | Modena, Italy | — |
| AOU Parma | Parma, Italy | — |
| Ospedale di Rimini, AUSL Romagna | Rimini, Italy | — |
Follow this study
Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.
We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT06790004