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Study identifier: NCT06769048 Synced from ClinicalTrials.gov · August 02, 2026
● Active Not Recruiting

A Study to Test Different Doses of BI 1584862 in People With a Distinct Form of Age-related Macular Degeneration (AMD) Called Geographic Atrophy

Condition: Geographic Atrophy  ·  Sponsor: Boehringer Ingelheim

PhasePhase 2
Planned participants150
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

This study is open to adults aged 50 years and older with geographic atrophy that was diagnosed by imaging of the retina. The purpose of this study is to find out whether a medicine called BI 1584862 improves the eyes in people with geographic atrophy and to find the most suitable dose. This study has 4 treatment groups. Participants are put into groups randomly, which means by chance. Initially participants can join a BI 1584862 and a placebo group; then more participants are put randomly in 2 additional BI 1584862 groups and a placebo group. Participants are in the study for 1 year. During this time, they visit the study site 13 times. At the visits, doctors check the severity of participants' eye disease and collect information on any health problems. They take detailed pictures of the back of the eye, the retina, with imaging methods called fundus autofluorescence (FAF), near-infrared reflectance (NIR), and optical coherence tomography (OCT). They measure areas of the retina that appear healthy (bright) or start to waste away (dark, atrophy). The changes over time are then compared between the treatment groups.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (44)

Associated Retina ConsultantsGilbert, Arizona, United States
Associated Retina Consultants, Ltd.Phoenix, Arizona, United States
Cameron Ria, LLCPhoenix, Arizona, United States
Retina Macula Institute of ArizonaScottsdale, Arizona, United States
Retina-Vitreous Associates Medical GroupBeverly Hills, California, United States
Global Research ManagementGlendale, California, United States
Retina Associates of Southern CaliforniaHuntington Beach, California, United States
Retinal Consultants Medical Group, IncModesto, California, United States
Northern California Retina Vitreous Associates MedicalGroup, Inc.Mountain View, California, United States
Eye Research FoundationNewport Beach, California, United States
Retina Consultants of San DiegoPoway, California, United States
Retinal Consultants Medical GroupSacramento, California, United States

+ 32 more locations — full list on the registry record.

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