EichorEICHOR
Study identifier: NCT06750094 Synced from ClinicalTrials.gov · August 02, 2026
● Recruiting

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

Condition: Colorectal Neoplasms  ·  Sponsor: Janssen Research & Development, LLC

PhasePhase 3
Planned participants700
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to compare how long the participants are disease-free (progression-free survival) and and the length of time until a participant dies (overall survival), when treated with amivantamab and chemotherapy with 5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovorin, and irinotecan hydrochloride (FOLFIRI) versus either cetuximab or bevacizumab and FOLFIRI given to participants with Kirsten rat sarcoma viral oncogene/ neuroblastoma RAS viral oncogene homolog (KRAS/ NRAS) and v-raf murine sarcoma viral oncogene homolog B (BRAF) wild-type recurrent, unresectable or metastatic colorectal cancer who have previously received chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Study Contact  ·  844-434-4210  ·  Participate-In-This-Study1@its.jnj.com

Always discuss trial participation with your own doctor first.

Locations (250)

Ironwood Cancer and Research CenterChandler, Arizona, United StatesRecruiting
Banner MD Anderson Cancer CenterGilbert, Arizona, United StatesRecruiting
Arizona Oncology Associates PC NAHOAPrescott, Arizona, United StatesCompleted
St. Bernard's Medical CenterJonesboro, Arkansas, United StatesRecruiting
Highlands Oncology GroupSpringdale, Arkansas, United StatesRecruiting
CBCC Global ResearchBakersfield, California, United StatesRecruiting
Los Angeles Cancer NetworkGlendale, California, United StatesRecruiting
Cancer and Blood Specialty ClinicLos Alamitos, California, United StatesRecruiting
USC Norris Comprehensive Cancer CenterLos Angeles, California, United StatesRecruiting
UCLASanta Monica, California, United StatesRecruiting
Providence Medical FoundationSanta Rosa, California, United StatesRecruiting
Torrance Memorial Physicians NetworkTorrance, California, United StatesRecruiting

+ 238 more locations — full list on the registry record.

Follow this study

Save your interest here for when the public record changes — results posted, or the study's status changes. Email alerts for this study aren't switched on yet.

We keep this only about this public record, and never email you without alerts being switched on. Want it removed at any time? Email hello@eichor.com. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →